May Reilly Parker

Having suffered a tough life ever since a child, May Reilly has been a survivor through thick and thin. At a very young age, her father's brother Horace was diagnosed with cancer and Horace pleaded with her father to kill him instead of letting him die a long and painful death. Her father ended up by killing his brother. Later on, her father ended up by leaving her and his wife. This would lead to May's mother blaming May for his departure. Years later, she would befriend Anna Watson.
One day she would fall in love with a rich man named Johnny Jerome and he would ask her to marry him, to which she responded with a 'yes'.

But a madly in love Ben Parker tells May that Johnny is a criminal. May believes that Ben is jealous and continues to date Johnny until he is caught by the police. May decides to change her attitude on 'Mr. Right', he doesn't have to be rich and powerful. So she begins to date Ben. The new couple would spend a lot of time with Ben's brother Richard and girlfriend Mary. They'd quickly become friends. Then the day arrived when they got married. Despite their love for children, they never felt the need to have any, espcially when Richard and Mary would have a baby in Peter. When a Rich and Mary's plane crashes, Ben and May are forced to take care of baby Peter and raise him by themselves. She would be overprotective towards Peter, but she only did this because she loved him so much.
After almost 15 years of taking care of her nephew, May's husband is shot dead when a burglar enters the Parker home looknig for remains of an old jewel heist. When May hears that Spider-Man caught the burglar, she feels that Spider-Man used that event to catapult his name to fame, thus making her distrust and loathe the Wall-Crawler ever since. One day, she would meet Anna's niece Mary Jane and she thought that she was the ideal girl for Peter. In fact, she was the one who set-up Peter to meet Mary Jane for the first time, because she knew that those two were meant to be with each other.
Her romance life is almost non-existant since, but she almost married Otto Octavius (a.k.a. Dr. Octopus). That was all part of a plot for Ock to gain valuable land that May owned. But something happened that Ock did not forsee, May understood him and he fell in love with her. He would show a lot of affection towards her later on after this incident. Later on, May would meet a man named Nathan Lubensky. Despite a gambling problem and his health deteriorating quite rapidly, May agreed to accept his mariage proposal. But one day at an outdoor show in Manhattan, the Vulture would strike and he would unknownly kidnap Nathan (a man who had helped the Vulture in the past) and take him up in the air. That would cause Nathan's heart to stop.
Many months later, the Vulture would find out that he's dying, he wanted forgiveness from May for killing Nathan. May, at first wouldn't give it to him, but in the end she did forgive him. Before that, the Vulture took Peter hostage. Peter manage to change into Spider-Man and defeat the villain. Spidey returned home with the Vulture so he can apologize to May for causing all that trouble. May asked Spidey, where is Peter. Spidey said that he's on his way. May kisses the hero. Then when May turns around, she sees him on the couch (a bit tired). Later, she would forgive Spider-Man for saying all those bad things about him during all those years.
When Peter's "parents" returned, she truly didn't believe that they were the real thing. She was the only one who doubted them. Shortly thereafter, she'd suffer a stroke. Unknowningly to everyone, Norman Osborn would "kidnap" her, and have her replaced by a dying actress. "May" would then awake from her coma and reveal to Peter that she knew for a long time that Peter has been Spider-Man. Then she'd die in her home. A year later (Marvel time), Spider-Man would figure out Osborn's plan and May would wake-up from her coma. Apparently, her coma caused some brain damage, because she doesn't remember forgiving Spider-Man. She is a very smart woman, who can be naive at times, but is insightful. She is currently living in her home at Forrest Hills.
On a night in which Peter has fought one of the most gruelling fights of his life, aunt May decides to stop by the Parker pad and what she finds out will change the rest of her life; she finds out that Peter is Spider-Man. She talks it out with her nephew and while she might not like it, she accepts the fact that her son is a hero and is even more proud of him than ever before. She even tries to convince newspapers like the Daily Bugle to stop publishing negative stories about that 'nice super-hero' Spider-Man. In an attempt to move on, she would decide to sell her house in Forrest Hills and rent an apartment in NYC, in order to be closer to Peter and MJ. More so than ever, May Parker is the heart and soul of Peter's life and serves as a reminder of why he does what he does.